Archive by category | Tuberculosis

Childhood tuberculosis treatment remains imprecise science

Childhood tuberculosis treatment remains imprecise science

By Julie Manoharan Last year, the World Health Organization released updated procedures on how best to tackle the global scourge of tuberculosis. The fourth edition of the “Treatment of tuberculosis: Guidelines” recommended, among other changes, increasing the dosage of tuberculosis medication required to treat children. But, in a sense, the new guidance provided a destination without a map: it failed to address the larger problem of how to improve the accuracy of pediatric dosing. In recent months, researchers have pointed to a host of problems plaguing the diagnosis and treatment of tuberculosis in children, especially those younger than age 5.  Read more

Good reason TB nervous

The case is undeniably bizarre. Man has deadly infection, health officials try in vain to get him to stop flying, he puts hundreds of passengers at risk despite being on a so-called “no-fly” list, a customs official lets him in because he doesn’t look sick… oh, and most bizarrely of all, his father-in-law is a researcher at the Centers for Disease Control and Prevention specializing in, wait for it, TB.  Read more

TB’s day in the sun

Well, sort of. For the past few days, I’ve been in rainy Vancouver, where TB researchers from all over the world have gathered for a Keystone meeting on the topic. As we reported in our free TB special this month, TB kills 4,400 people every day and together with HIV, is creating a serious crisis in Africa, Asia and eastern Europe.  Read more

TB or not TB

Did you know that although AIDS and TB kill about the same number of people, AIDS research gets roughly 20 times the money given for TB research? I didn’t either, until I went to a meeting last week organized by MSF (Doctors without Borders). The theme of the meeting was the urgent need to get some more money—a common cry in science, but in this case, fully warranted.  Read more

Going after Gates

When I worked at Fred Hutchinson Cancer Research Center in Seattle I was struck by the chemicals researchers routinely tossed away—often down the drain. It seemed paradoxical that the attempt to understand cancer involved the manufacture of some nasty carcinogens.  Read more