Q. I plan to submit a research article to Nature, but I am not sure what is difference between Nature article and letter. I notice there is usually only one article per issue of Nature, but several letters. I do not know how to decide to submit a manuscript as an article format or as a letter format. Would you please explain this to me?
A. Articles are original reports whose conclusions represent a substantial advance in understanding of an important problem and have immediate, far-reaching implications.
Letters are short reports of original research focused on an outstanding finding whose importance means that it will be of interest to scientists in other fields.
More details are available at the journal’s guide to authors and at the Nature Publishing Group author and reviewers’ website, where there is a description of the article types published in all the Nature journals.