Check out Nature Methods’ February 2008 issue, featuring several methodological aspects of structural genomics and structural biology. A Commentary provides an overview of the efforts of the US-based Protein Structure Initiative, a Review from multiple, worldwide structural genomics consortia provides a consensus strategy for expressing and purifying recombinant proteins, a Perspective provides a user-friendly guide to protein crystallization, and the Technology Feature shows a day in the life of a structural genomics facility. Additionally, the Editorial discusses some of the criticisms that structural genomics efforts have faced, as well as some of the beneficial results.
What are your thoughts about structural genomics? Share your comments here!